There are numerous choices when it comes to picking a PCB fabrication company. I’ve been using ExpressPCB since their software is very easy to use. The problem with ExpressPCB is the software is proprietary to their manufacturing services. They do allow you the opportunity to purchase your board files in order to have them produced by other PCB fabrication companies, however, you have to purchase a set from them first.
There are other popular options for schematic/PCB software that does not lock you into their services. Two popular applications are Eagle and Diptrace. The problem is deciding what fabrication company to use in order to have your boards produced. Digital DIY has put together an in-depth article comparing some of the many services that are offered.
Read about it here: Digital DIY